All of Us Notice Outlines Future Technology Needs to Support the Program’s Growth

November 18, 2022
Three university students meet around a laptop computer.

Potential applicants are encouraged to learn more ahead of Research Opportunity Announcement

The National Institutes of Health’s All of Us Research Program is planning for a new Participant and Partner Services Center (PPSC) to enhance participant engagement, enrollment, and retention. A Notice of Future Research Opportunity Announcement (NOT-PM-23-001) outlines the anticipated support and expertise envisioned for the PPSC to provide potential applicants time to engage with the program in advance of the release of a Research Opportunity Announcement (ROA) in early 2023. The PPSC will bring new and refined technology and research capabilities to support the program’s growth.

“The first five years of the program have been crucial for developing a solid infrastructure and foundation for All of Us,” said Chris Lunt, chief technology officer, All of Us Research Program. “We are looking for new solutions that will leverage the strengths of the program and provide a platform to continue to grow and evolve our efforts and support for program partners and participants.”

The All of Us Research Program has enrolled more than 545,000 adult participants and assembled an awardee partner network of more than 100 organizations supporting community outreach and engagement, participant enrollment and retention, study operations, and long-term program management. The PPSC will encompass the program’s Participant Technology Systems Center (PTSC), which currently provides tools and platforms that help participants enroll in the program, share their health information, and receive program updates. Any proposed technology systems and research services for the PPSC must be capable of integrating with current All of Us participant platforms. The selected proposal will be responsible for transitioning existing data integrations with other All of Us partners and the scope of the current PTSC award. 

Through the PPSC, the program aims to broaden support for its continuously evolving set of enrollment partners, participants (including children and adolescents in the future), data collection methods, ancillary study integration, and return of information to participants. The PPSC will provide essential program support and enhanced functions including:

  • Supporting nationwide enrollment locations and networks 

  • Sustaining support for, and retention of, a large, diverse, nationally distributed cohort

  • Enhancing the participation experience across All of Us’ participants, including those from different cultural backgrounds, education levels, and health statuses

  • Enabling new data collection methods for participant participation

  • Providing translation, and supporting implementation of the research protocol in multiple languages 

  • Integrating new technology, methods, and services for participant data collection, including environmental monitoring  

A full list of currently identified and prioritized capabilities and services are outlined in the notice

Potential partners are encouraged to inquire with the program to better understand the capabilities needed in advance of the release of the ROA. Inquiries can be emailed to, using subject: PPSC Notice (NOT-PM-23-001). 

All of Us is a registered service mark of the U.S. Department of Health & Human Services (HHS).