NIH’s All of Us Research Program Awards $1.5 Million to Institutions Collaborating with Tribal Communities to Advance Precision Medicine

September 26, 2023
Native American woman on Tribal land stands outside.

Awardees in Arizona, Wisconsin, and New Mexico to work with American Indian/Alaska Native communities

The National Institutes of Health’s All of Us Research Program announced three awards totaling $1.5 million to institutions partnering with American Indian and Alaska Native (AI/AN) and Indigenous communities to advance health equity and precision medicine.

The awards have been made to the University of Arizona, the Marshfield Clinic Research Institute in Wisconsin, and the American Indian Science and Engineering Society (AISES). The awards will support outreach and engagement with Tribal and Indigenous communities, strengthen the research infrastructure supporting AI/AN researchers, and broaden the base of researchers conducting cultural and ethical research with Tribal communities. Additional funding opportunities are still available through May 2025.

“These collaborations are part of a long journey to co-create an environment of trust and to advance with Tribal communities on our shared goals of delivering a healthier future,” said Karriem Watson, D.H.Sc., M.S., M.P.H., All of Us chief engagement officer.

The awardees will lead several new efforts to engage AI/AN and Indigenous communities and researchers:

  • The University of Arizona team will develop a Community Readiness Assessment tool to support a long-term strategic plan for continued Tribal engagement. The partnership will offer insights into Tribes’ and other community partners’ readiness and interest in participation in the All of Us Research Program. The team will collaborate with a Community Advisory Committee (CAC) composed of Tribal and AI/AN urban center leaders, traditional healers, health care executives, and content experts. 
  • The Marshfield Clinic Research Institute team will co-develop long-term collaborative partnerships with Wisconsin Tribal representatives, including urban Indian communities in Milwaukee. The award also aims to expand medical research within AI/AN communities by providing training opportunities and expanding the AI/AN-led precision medicine research infrastructure. 
  • The American Indian Science and Engineering Society (AISES), a national nonprofit focused on increasing representation of Indigenous peoples in science, will design a multi-media outreach campaign “We Are All Scientists” to promote health research with Indigenous students, and to increase opportunities and support career enhancement pathways for students, educators, and research scientists.  

“We’re committed to working together to make All of Us an inclusive program that benefits AI/AN and Indigenous participants and their communities,” said Michael Hahn, All of Us Tribal Engagement and Outreach Branch Chief. “Through these awards, we aim to build more partnerships with Tribal communities, elevate the diverse perspectives of Indigenous people to guide program plans, and ultimately enable more research about Indigenous health by Indigenous researchers.”

These awards are an extension of the program’s ongoing Tribal engagement activities, which also include formal Tribal Consultations and information sessions. On September 28, 2023, All of Us will host its next Consultation online to receive feedback from Tribal leaders on program initiatives. The virtual meeting will include an update on Tribal engagement activities and overall program plans, as well as a discussion on the integration of data from self-identified AI/AN participants into the program's data platform, the All of Us Research Hub. Tribal leaders may also submit written input on these items by October 28 to

All of Us aims to build one of the largest and most diverse biomedical resources in history, with at least one million participants nationwide. This large dataset can allow researchers to study health and disease for a broader population and change the one-size-fits-all standard health care approach. The program has a special focus on engaging AI/AN communities interested in medical research, to close information gaps and help increase health equity.

About the All of Us Research Program: The mission of the All of Us Research Program is to accelerate health research and medical breakthroughs, enabling individualized prevention, treatment, and care for all of us. The program will partner with one million or more people across the United States to build the most diverse biomedical data resource of its kind, to help researchers gain better insights into the biological, environmental, and behavioral factors that influence health. For more information, visit and

About the National Institutes of Health (NIH): NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit