Purpose
The All of Us Research Program Reflection and Advancement Working Group, a working group of the All of Us Research Program Advisory Panel, was charged with assessing the program’s evolution, evaluating achievements, challenges, and opportunities for improvement and advancement since the national launch in 2018. The Working Group provided an assessment and identified opportunities in order to shape the program's strategic plan towards maximizing its scientific impact and trajectory leading up to 2031.
Deliverable
The Working Group convened a series of working sessions to discuss and write a report to lay the groundwork for shaping the next iteration and extension of the All of Us strategic plan, with a forward-looking vision aimed at maximizing the program's impact leading up to 2031. Key questions deliberated in this report included:
Charting Progress: Key Metrics and Program Differentiators
- Given the vision outlined in the 2015 Advisory Committee to the NIH Director Working Group Report, which key indicators or metrics best reflect the program’s progress and success thus far?
- What are the most important differentiators of the program? What is, or should be, All of Us uniquely positioned to achieve?
Cultivating Established Trust: Future Growth Opportunities for All of Us
- Where are there opportunities for growth or areas for improvement within the program?
- How can the program amplify the trust established among diverse participants, expanding their engagement and leveraging their involvement and voices?
Ensuring Health Equity: The Current and Future Impact of All of Us as a National Resource
- What is the impact of the All of Us Research Program and what are the best opportunities for it to change the equitable practice of medicine now and in the future?
- As the program exceeds 800K participants, and 10K researchers, how should the program focus its future investments to sustain and grow as a vital national research resource?
Envisioning the Future: The Sustainability and Longitudinality of All of Us
- What prospective actions can All of Us take to minimize long-term infrastructure costs to taxpayers while improving overall efficiency and effectiveness?
- How can All of Us strategically contribute to future cost savings for researchers within the scientific ecosystem, leveraging initiatives like the passport and cloud model?
A summary of key findings from the report was presented at the September 2024 Council of Councils meeting.
Roster
Chairs
Russ Altman, M.D., Ph.D., Working Group Chair
Stanford University
Kenneth Fong Professor of Bioengineering, Genetics, Medicine, Biomedical Data Science and (by courtesy) Computer Science
Marylyn DeRiggi Ritchie, Ph.D., M.S., Working Group Vice Chair
Edward Rose, M.D. and Elizabeth Kirk Rose, M.D. Professor of Genetics
Vice President for Research Informatics Director of the Institute for Biomedical Informatics
Director for the Division of Bioinformatics, Department of Biostatistics
Vice Dean of Artificial Intelligence and Computing
Rhonda Robinson Beale, M.D., Working Group Vice Chair
UnitedHealth Group
Senior Vice President, Mental Health Services
Deputy Chief Medical Officer, Mental Health Service
Members
Aaron Abend, M.B.A.
Autoimmune Registry, Inc.
Executive Director
Naomi Allen, D.Phil., M.Sc., B.Sc.
UK Biobank
Chief Scientist
University of Oxford
Professor of Epidemiology, Nuffield Department of Population Health
Wendy Chung, M.D., Ph.D.
Boston Children’s Hospital
Chief of the Department of Pediatrics
Harvard Medical School
Professor of Pediatrics
Gary Miller, Ph.D., M.S.
Columbia University Mailman School of Public Health
Vice Dean, Research Strategy and Innovation
Christopher O’Donnell, M.D., M.P.H., FAHA, FACC
Cardiovascular & Metabolism at Novartis Institutes for Biomedical Research
Global Head of Translational Medicine
Elizabeth O. Ofili, M.D., M.P.H., F.A.C.C.
Morehouse School of Medicine
Professor of Medicine
Morehouse Healthcare
Practicing Cardiologist
Evelyn Ortiz
New York City Housing Authority, Retired
Health Equity Advocate
Participant Ambassador, All of Us Research Program
Jesus Ramirez-Valles, Ph.D., M.P.H.
University of California San Francisco
Chief of the University of California San Francisco Division of Prevention Science
Scout, Ph.D., M.A.
National LGBT Cancer Network
Executive Director
Prashant Shah, M.S.
Intel Corporation
Director of Engineering of Health and Life Sciences
Artificial Intelligence Products Group
Hannah Valentine, M.D., M.R.C.P.
Stanford University
Professor of Medicine
National Institutes of Health
Former Chief Officer for Scientific Workforce Diversity
Roberto Vargas, M.D., M.P.H.
Charles R. Drew University of Medicine and Science
Assistant Dean, Health Policy and Inter-Professional Education, College of Medicine
Charles R. Drew University of Medicine and Science
Director, Health Policy Pillar of the Urban Health Institute
Xiaobin Wang, M.D., Sc.D., M.P.H.
Johns Hopkins Bloomberg School of Public Health and School of Medicine
Zanvyl Krieger Professor In Children's Health
Professor of Pediatrics
Director, Center on the Early Life Origins of Disease
Ex Officio Members
Sadiqa Mahmood, D.D.S., M.P.H.
Health Catalyst
General Manager and Senior Vice President
Josh Mandel, M.D.
Harvard Medical School
Lecturer on Biomedical Informatics
Chief Architect, SMART Health IT
Chief Architect, Microsoft Healthcare
Elizabeth Rubinstein
Patient Advisor, Henry Ford Health System Board of Directors Quality and Safety Committee
Advisor, All of Us TACH Organ Procurement Organization
Former Participant Ambassador, All of Us Research Program
Karen Wall, Ed.D., M.A.
U.S. Army Nurse Corps
Major, Retired (Operation Desert Storm Combat Veteran)
Western Institute for Social Research
Graduate Professor, Marriage and Family Therapy
Former Participant Ambassador, All of Us Research Program
All of Us Research Program Support Members
Rachele Peterson, M.S., M.B.A.
National Institutes of Health
Chief of Staff
Hannah Coleman, M.S.W.
Axle Informatics
Special Assistant to the Chief of Staff
Victoria Palacios, M.P.H.
Leidos
Biomedical Life Scientist